Comparative transcriptome analysis reveals a regulatory network of microRNA-29b during mouse early embryonic development


MicroRNAs are endogenous ~22 nt RNAs that regulate gene expression by translational inhibition and mRNA destabilization. MicroRNA-29b (miR-29b) is essential for progression of mouse embryos past preimplantation development; however, details of the underlying regulatory network remain to be elucidated. Here, we used RNA sequencing to identify changes in the… (More)
DOI: 10.18632/oncotarget.10741