Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei.

@article{Zheng2013ComparativeTA,
  title={Comparative transcriptome analysis of small noncoding RNAs in different stages of Trypanosoma brucei.},
  author={Ling-Ling Zheng and Yan-Zi Wen and Jianhua Yang and Jian-You Liao and Peng Shao and Hui Xu and Hui Zhou and Jun-Zhi Wen and Zhao-rong Lun and Francisco J. Ayala and Liang-Hu Qu},
  journal={RNA},
  year={2013},
  volume={19 7},
  pages={863-75}
}
Trypanosoma brucei, a pathogen of human and domestic animals, is an early evolved parasitic protozoan with a complex life cycle. Most genes of this parasite are post-transcriptionally regulated. However, the mechanisms and the molecules involved remain largely unknown. We have deep-sequenced the small RNAs of two life stages of this parasite--the bloodstream form and the procyclic form. Our results show that the small RNAs of T. brucei could derive from multiple sources, including NATs (natural… CONTINUE READING
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