Comparative toxicokinetics of inhaled methanol in the female CD-1 mouse and Sprague-Dawley rat.

@article{Perkins1995ComparativeTO,
  title={Comparative toxicokinetics of inhaled methanol in the female CD-1 mouse and Sprague-Dawley rat.},
  author={Robert A. Perkins and Keith W. Ward and Gary M. Pollack},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1995},
  volume={28 2},
  pages={245-54}
}
Female CD-1 mice were exposed for 8 hr, both individually and in groups of eight to nine, to 2500, 5000, and 10,000 ppm methanol vapor in a flowthrough exposure chamber. The ventilation of individually exposed mice and the absorption of methanol from the chamber airstream were measured. The extraction of methanol from the airstream and the blood methanol concentration at various time points during and following exposure were determined for the group-exposed mice. The similarity of systemic… CONTINUE READING

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