Comparative toxicokinetics of explosive compounds in sheepshead minnows.

  title={Comparative toxicokinetics of explosive compounds in sheepshead minnows.},
  author={Guilherme R Lotufo and Michael J Lydy},
  journal={Archives of environmental contamination and toxicology},
  volume={49 2},
Juvenile sheepshead minnows Cyprinodon variegatus were exposed to the explosive compounds 2,4,6-trinitrotoluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) and to the TNT transformation products 2-aminodinitrotoluene (2-ADNT) and 2,4-diaminonitrotoluene (2,4-DANT) in five separate water-only experiments. A one-compartment model was used to characterize uptake (k(u)) and elimination (k(e)) rate constants and to estimate… CONTINUE READING