Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells.

@article{Naranmandura2011ComparativeTO,
  title={Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells.},
  author={Hua Naranmandura and Michael W. Carew and Shi Ye Xu and Jane HyoJin Lee and Elaine M. Leslie and Michael Weinfeld and X Chris Le},
  journal={Chemical research in toxicology},
  year={2011},
  volume={24 9},
  pages={1586-96}
}
The human bladder is one of the primary target organs for arsenic-induced carcinogenicity, and arsenic metabolites in urine have been suspected to be directly involved in carcinogenesis. Thioarsenicals are commonly found in human and animal urine and are also considered to be highly toxic arsenic metabolites. The present study was performed to gain insight into the toxicity and accumulation of arsenic species found in urine, including arsenate (iAs(V)), arsenite (iAs(III)), monomethylarsonic… CONTINUE READING