Comparative teratogenicity of chlorpyrifos and malathion on Xenopus laevis development.

@article{Bonfanti2004ComparativeTO,
  title={Comparative teratogenicity of chlorpyrifos and malathion on Xenopus laevis development.},
  author={P. Bonfanti and A. Colombo and F. Orsi and Ilaria Nizzetto and Manuela Andrioletti and R. Bacchetta and P. Mantecca and U. Fascio and G. Vailati and C. Vismara},
  journal={Aquatic toxicology},
  year={2004},
  volume={70 3},
  pages={
          189-200
        }
}
The embryotoxic potential of chlorpyrifos (CPF) and malathion (MTN), two organophosphorus insecticides (OPs), was evaluated by modified Frog Embryo Teratogenesis Assay-Xenopus (FETAX). CPF and MTN were not embryolethal even at the highest concentration tested (6000 microg/l), but both exhibited a powerful teratogenicity. The probit analysis of malformed larva percentages showed a TC(50) of 161.54mug/l for CPF, and a TC(50) of 2394.01 microg/l for MTN. Therefore, CPF teratogenicity was about 15… Expand
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  • 7
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  • 33
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References

SHOWING 1-10 OF 53 REFERENCES
Osteolathyrogenic effects of malathion in Xenopus embryos.
  • 41
Biochemical effects of chlorpyrifos on two developmental stages of Xenopus laevis.
  • 52
  • Highly Influential
In vivo and in vitro resistance to multiple anticholinesterases in Xenopus laevis tadpoles.
  • 22
Toxic and developmental effects of organophosphorus insecticides in embryos of the South African clawed frog.
  • J. Snawder, J. Chambers
  • Biology, Medicine
  • Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
  • 1989
  • 50
  • Highly Influential
Morphological abnormalities in African catfish (Clarias gariepinus) larvae exposed to malathion.
  • 66
The role of glutathion conjugation in the regulation of early toad embryos' tolerance to pesticides.
  • 39
The sensitivity of grass shrimp, Palaemonetes pugio, embryos to organophosphate pesticide induced acetylcholinesterase inhibition.
  • 39
Development of a metabolic activation system for the frog embryo teratogenesis assay: Xenopus (FETAX).
  • 71
Acetylcholinesterase inhibition in estuarine fish and invertebrates as an indicator of organophosphorus insecticide exposure and effects.
  • M. Fulton, P. Key
  • Biology, Medicine
  • Environmental toxicology and chemistry
  • 2001
  • 607
Further validation of FETAX: evaluation of the developmental toxicity of five known mammalian teratogens and non-teratogens.
  • 76
...
1
2
3
4
5
...