Comparative study on the pathogenicity and immunogenicity of wild bird isolates of avian paramyxovirus 2, 4, and 6 in chickens.

  title={Comparative study on the pathogenicity and immunogenicity of wild bird isolates of avian paramyxovirus 2, 4, and 6 in chickens.},
  author={Ashwini Warke and David E. Stallknecht and Susan M. Williams and Nikki Pritchard and Egbert Mundt},
  journal={Avian Pathology},
  pages={429 - 434}
Based on the haemagglutination inhibition assay, nine antigenically distinct serotypes of avian paramyxoviruses (APMV) are described. Isolates from APMV 2, 3, 6 and 7 can cause respiratory symptoms and/or problems of the reproductive tract that may produce complications if secondary infections occur, while isolates from APMV 4, 5, 8 and 9 rarely produce clinical signs in species from which they are isolated. Isolates belonging to the APMV 1 subtype induce a wide range of disease symptoms… 
Experimental Infection of Mice with Avian Paramyxovirus Serotypes 1 to 9
All APMV serotypes except apMV-5 are capable of replicating in mice with minimal disease and pathology, and are demonstrated to be a potential vector for human vaccines.
Evaluation of the replication and pathogenicity of a variant avian paramyxovirus serotype 6 in mice
It is found that the variant and prototype strains of APMV-6 could similarly replicate in respiratory tissues of infected mice and induce respiratory disease, sometimes resulting in death of the mice.
Experimental infection of hamsters with avian paramyxovirus serotypes 1 to 9
All nine known APMV serotypes are capable of replicating in hamsters with minimal disease and pathology, and all of the APMVs produced serotype-specific HI or neutralizing antibodies, confirming virus replication.
Pathogenesis of Two Strains of Avian Paramyxovirus Serotype 2, Yucaipa and Bangor, in Chickens and Turkeys
The pathogenicity of two strains of APMV-2, Yucaipa and Bangor, are examined in 9-day-old embryonated chicken eggs, 1- day-old specific-pathogen-free (SPF) chicks, and 4-wk-old SPF chickens and turkeys, indicating that these viruses are nonpathogenic in chickens.
Epidemiological Studies of Avian Paramyxovirus Type 4 and 6 in Commercial Chicken Flocks in Korea
It is concluded that wild bird-origin APMV type 4 and 6 could infect the chickens by inter-species transmission and the seroprevalence of APMv type 4 was quite high in Korean poultry.
Dispersal and Transmission of Avian Paramyxovirus Serotype 4 among Wild Birds and Domestic Poultry
Findings from an APMV-4 surveillance in six provinces of China suggest potential virus interspecies transmission between wild birds and domestic poultry, and reveal possible epidemiological intercontinental connections between APMv-4 transmission by wild birds.
Genetic and evolutionary characterization of avian paramyxovirus type 4 in China.
  • Qingxun Zhang, Jie Liu, Hongxuan He
  • Biology
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
  • 2021
Circulation of avian paramyxoviruses in wild birds of Kazakhstan in 2002–2013
This is the first reported characterization of avian paramyxoviruses from wild birds isolated in Kazakhstan, and data confirm the wide distribution of APMV-1, APmV-4 and APMv-6 in the Asian subcontinent.
The first investigations with avian blood sera in Bulgaria to detect antibodies against APMV-2 showed spread of infection among hens and chickens with 14.53 % positive samples, and presence of infection in all surveyed farms.
Pathogenicity of Avian Paramyxovirus Serotype-3 in Chickens and Turkeys
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Avian paramyxoviruses serotype 3 isolated from captive birds in Israel: clinical signs, pathology, and antigenic characterization.
This is the first isolation of APMV-3 from birds belonging to the orders Anseriformes and Ciconiiformes, and it was found that the isolates were more close antigenically to the APMv-3b variety (prototype strain--APM V-3/Parakeet/Netherlands/449/75) than to theAPMV -3a variety ( prototype strain)--APMVs3/Turkey/Wisconsin/68.
Isolation of avian serotype 3 paramyxoviruses from imported caged birds in Israel.
Ten avian serotype 3 paramyxoviruses were isolated for the first time in Israel from passerine and psittacine imported caged birds, and only the parakeets developed specific neurologic signs.
Prevalence of antibodies to avian paramyxoviruses 1, 2 and 3 in wild and domestic birds in southern Spain.
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Serological Survey on the Prevalence of Antibodies to Avian Paramyxovirus Serotype 2 in China
This study investigated the prevalence of avian paramyxovirus serotype 2 (APMV-2) antibodies from different regions and from different avian species in China and suggested that the incidence of APMV2 antibodies was very high in differentAvian species and in most of sampled areas.
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Isolation of a new avian paramyxovirus from budgerigar (Melopsittacus undulatus).
The Kunitachi viruses including three strains recently isolated from the same host were found to be serologically distinct from the known paramyxovirus strains and appeared to constitute a new subtype of avian paramyxvirus.
Isolation and properties of viruses from poultry in Hong Kong which represent a new (sixth) distinct group of avian paramyxoviruses.
Eight viruses isolated in Hong Kong were shown to be serologically related but were serologically distinct from other avian and mammalian paramyxoviruses by haemagglutination inhibition and neuraminidase inhibition tests.
Natural and experimental infection of turkeys with avian paramyxovirus-7.
Avian paramyxovirus-7 was isolated from a natural outbreak of respiratory tract disease in male and female commercial turkey breeder flocks, and hemagglutination inhibition antibodies were detected in exposed birds.
Serological Survey on Prevalence of Antibodies to Avian Paramyxovirus Serotype 2 in China
The results of this survey indicate that the distribution of APMV-2 is very widespread in China and that more attention should be paid to the influence of the virus on poultry production.
Effect of paramyxovirus yucaipa on fertility, hatchability, and poult yield of turkeys.
A controlled field trial conducted in 1966 in turkey breeder hens intentionally infected with PMY virus found that the hens in all 8 pens retained a high level of fertility, hatchability, and poult yield.