Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom.

@article{Gen1989ComparativeSO,
  title={Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom.},
  author={J A Gen{\'e} and Annie Roy and Gustavo Adolfo Rojas and Jos{\'e} Mar{\'i}a Guti{\'e}rrez and L Cerdas},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={1989},
  volume={27 8},
  pages={841-8}
}
The coagulant, defibrinating, fibrino lytic and fibrinogenolytic activities of venoms from ten species of Costa Rican crotaline snakes were studied, together with the neutralization of these effects by a polyvalent antivenom. The venoms of Bothrops asper, B. schlegelii, B. nummifer, B. godmani, Lachesis muta and Crotalus durissus induced a coagulant effect in vitro, and all of them, with the exception of B. nummifer, also induced defibrination in vivo. The four non-coagulant venoms (B… CONTINUE READING
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