Comparative study of the lubricant performance of Compritol 888 ATO either used by blending or by hot melt coating.

@article{Jannin2003ComparativeSO,
  title={Comparative study of the lubricant performance of Compritol 888 ATO either used by blending or by hot melt coating.},
  author={Vincent Jannin and V{\'e}ronique B{\'e}rard and A N'diaye and Cyrille Andr{\`e}s and Y Pourcelot},
  journal={International journal of pharmaceutics},
  year={2003},
  volume={262 1-2},
  pages={39-45}
}
Compritol 888 ATO is used as a lubricant in oral solid dosage formulations. It can also be used as a hot melt coating agent sprayed onto a powder. In this study, we compare the lubricant performance of Compritol 888 ATO either used by classical blending or by hot melt coating onto Lactopress by compression tests. In physical mix, the Compritol concentration does not affect the compressibility. The same compressibility is obtained with lactose coated by 0.5 or 1% of Compritol, but a higher… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…