Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial.

@article{Lucasti2013ComparativeSO,
  title={Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial.},
  author={Christopher Lucasti and Irinel E. Popescu and Mayakonda Krishnamurthy Ramesh and Joy Lipka and Carole A. Sable},
  journal={The Journal of antimicrobial chemotherapy},
  year={2013},
  volume={68 5},
  pages={
          1183-92
        }
}
OBJECTIVES Avibactam, a novel non-β-lactam β-lactamase inhibitor, restores the in vitro activity of ceftazidime against class A, C and some class D β-lactamase-producing pathogens, including those commonly associated with complicated intra-abdominal infections (cIAIs). This randomized, active-controlled, double-blind, Phase II trial (NCT00752219) aimed to evaluate the safety and efficacy of ceftazidime/avibactam plus metronidazole compared with meropenem in hospitalized patients with cIAI… CONTINUE READING
Tweets
This paper has been referenced on Twitter 6 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 61 CITATIONS, ESTIMATED 61% COVERAGE

102 Citations

0102030'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 102 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES

Similar Papers

Loading similar papers…