Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen

@inproceedings{Xu2016ComparativeSO,
  title={Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen},
  author={Jiawei Xu and Wenbin Niu and Zhaofeng Peng and Xiao Zhao Bao and Meixiang Zhang and Linlin Wang and Linqing Du and Nan Zhang and Ying-pu Sun},
  booktitle={Oncotarget},
  year={2016}
}
Triploidy occurred about 2-3% in human pregnancies and contributed to approximately 15% of chromosomally caused human early miscarriage. It is essential for preimplantation genetic diagnosis and screen to distinct triploidy sensitively. Here, we performed comparative investigations between MALBAC-NGS and MDA-SNP array sensitivity on triploidy detection… CONTINUE READING