Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area.

@article{Hamilton2001ComparativeSO,
  title={Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area.},
  author={Jennifer D D Hamilton and Iain B. Mcinnes and Evelyn Thomson and Duncan R Porter and John A. A. Hunter and Rajneesh Madhok and Hilary A Capell},
  journal={Annals of the rheumatic diseases},
  year={2001},
  volume={60 6},
  pages={566-72}
}
OBJECTIVE To compare the risk-benefit ratio of intramuscular gold (gold sodium thiomalate (GST)) and methotrexate (MTX) in a population with rheumatoid arthritis (RA) from a deprived area. METHODS Patients with active RA were randomly assigned to open treatment with GST or MTX. Clinical and laboratory assessment was performed at 0, 12, 24, and 48 weeks. Results were analysed on an intention to treat basis. RESULTS 141 patients were recruited-72 were randomly allocated to GST and 69 to MTX… CONTINUE READING

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