Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts.

@article{StreckfussBmeke2013ComparativeSO,
  title={Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts.},
  author={Katrin Streckfuss-B{\"o}meke and Frieder Wolf and Azadeh Azizian and Michael Stauske and Malte Tiburcy and Stefan Wagner and Daniela H{\"u}bscher and Ralf Dressel and Simin Chen and J{\"o}rg Jende and Gerald G. Wulf and Verena Natalie Lorenz and Michael P. Sch{\"o}n and Lars S. Maier and Wolfram-Hubertus Zimmermann and Gerd Hasenfuss and Kaomei Guan},
  journal={European heart journal},
  year={2013},
  volume={34 33},
  pages={
          2618-29
        }
}
AIMS Induced pluripotent stem cells (iPSCs) provide a unique opportunity for the generation of patient-specific cells for use in disease modelling, drug screening, and regenerative medicine. The aim of this study was to compare human-induced pluripotent stem cells (hiPSCs) derived from different somatic cell sources regarding their generation efficiency and cardiac differentiation potential, and functionalities of cardiomyocytes. METHODS AND RESULTS We generated hiPSCs from hair keratinocytes… 
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Tissue-Restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview.
TLDR
This review presents an overview of promising tissue-restricted stem cells that can be isolated from different sources, namely, neural stem cells, hematopoietic stem Cells, mesenchymalstem cells, limbal epithelial stem cells), and spermatogonial stem cells and their reprogramming efficacy.
A Comparative View on Human Somatic Cell Sources for iPSC Generation
TLDR
The advantages of keratinocytes from human plucked hair are highlighted as a widely usable, noninvasive harvesting method for primary material in comparison with other commonly used cell types.
A circular RNA map for human induced pluripotent stem cells of foetal origin
Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools
TLDR
This work aims at focusing on the protocols for differentiation of hPSCs into functional cardiomyocytes in vitro as well as achievements in the heart disease modelling and drug testing on the patient-specific iPSC-derivedCardiomyocyte-CMs.
Reprogramming of Keratinocytes as Donor or Target Cells Holds Great Promise for Cell Therapy and Regenerative Medicine
TLDR
Recent advances in keratinocyte reprogramming are discussed, focusing on the induction methods, potential molecular mechanisms, conversion efficiency, and safety for clinical applications.
An Overview on Promising Somatic Cell Sources Utilized for the Efficient Generation of Induced Pluripotent Stem Cells.
TLDR
This review provides an overview of promising easily accessible somatic cell sources isolated in non-invasive or minimally invasive manner such as keratinocytes, urine cells, and peripheral blood mononuclear cells used for the generation of human iPSCs derived from healthy and diseased subjects.
Differentiation of blood T cells: Reprogramming human induced pluripotent stem cells into neuronal cells
Induced pluripotent stem cells for cartilage repair: current status and future perspectives.
TLDR
iPSCs emerge as a promising cell source for treating cartilage defects and have the potential to be used in the clinical field, and a review summarises the recent progress in iPSC technology and its applications for cartilage repair.
Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
TLDR
It is proved that hair follicles could be used to produce pluripotent stem cells and suggested that the genetic and micro-environmental elements ofhair follicles might trigger higher and more efficient hair follicle re-differentiation.
Cardiac progenitors derived from reprogrammed mesenchymal stem cells contribute to angiomyogenic repair of the infarcted heart
TLDR
Efficient reprogramming of multipotent bone marrow (BM) mesenchymal stem cells (MSC) to pluripotent status and the resultant MSC derived iPS cells (MiPS) and their derived progenitors effectively repaired the infarcted heart.
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References

SHOWING 1-10 OF 28 REFERENCES
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
TLDR
It is shown that reprograming of juvenile human primary keratinocytes by retroviral transduction with OCT4, SOX2, KLF4 and c-MYC is at least 100-fold more efficient and twofold faster compared with reprogramming of human fibroblasts.
Generation of induced pluripotent stem cells by efficient reprogramming of adult bone marrow cells.
TLDR
It is shown that mouse adult bone marrow mononuclear cells (BM MNCs) are competent as donor cells and can be reprogrammed into pluripotent ES cell-like cells, implying that BM M NCs have potential advantages to generate iPS cells for the clinical application.
Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
TLDR
It is concluded that human iPS cells are a viable option as an autologous cell source for cardiac repair and a powerful tool for cardiovascular research.
Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature
TLDR
It is demonstrated that induced pluripotent stem cells (iPSCs) can be derived from murine ventricular myocytes (VMs), and consistent with other reports of iPSCs derived from various somatic cell types, VM-derived iPSC-derived ViPSCs (ViPSC) exhibit a markedly higher propensity to spontaneously differentiate into beating cardiomyocytes as compared to genetically matched embryonic stem cells or iPSCS derived from tail-tip fibroblasts.
Reprogramming of human somatic cells to pluripotency with defined factors
TLDR
The data demonstrate that defined factors can reprogramme human cells to pluripotency, and establish a method whereby patient-specific cells might be established in culture.
Reprogramming of Pancreatic β Cells into Induced Pluripotent Stem Cells
Generation of Functional Cardiomyocytes From Adult Mouse Spermatogonial Stem Cells
TLDR
MaGSCs provide a new source of distinct types of cardiomyocytes for basic research and potential therapeutic application, and it is believed that these cultured maG SCs were able to proliferate and differentiate into normal hearts of mice and no tumor formation was found up to 1 month after cell transplant.
Generation of induced pluripotent stem cells from human cord blood.
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Somatic cell nuclear transfer allows trans-acting factors present in the mammalian oocyte to reprogram somatic cell nuclei to an undifferentiated state. We show that four factors (OCT4, SOX2, NANOG,…
Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette
TLDR
Using a single lentiviral vector expressing a “stem cell cassette” composed of the four transcription factors and a combination of 2A peptide and internal ribosome entry site technology achieves the most efficient reprogramming system to date and allows derivation of iPS cells with a single viral integration.
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