Comparative study of epidermal growth factor receptor mutation analysis on cytology smears and surgical pathology specimens from primary and metastatic lung carcinomas.

@article{Khode2013ComparativeSO,
  title={Comparative study of epidermal growth factor receptor mutation analysis on cytology smears and surgical pathology specimens from primary and metastatic lung carcinomas.},
  author={Renu Khode and Douglas A Larsen and Brianne C Culbreath and Shane Parrish and Kimberly L Walker and Lubna Sayage-Rabie and Robert S. Beissner and Arundhati Rao},
  journal={Cancer cytopathology},
  year={2013},
  volume={121 7},
  pages={361-9}
}
BACKGROUND The detection of epidermal growth factor receptor (EGFR) mutations on small biopsy or fine-needle aspiration samples is required to guide therapy in nonsmall cell lung cancer (NSCLC). In this study, the authors compared results from EGFR mutation testing on both cytologic smears and surgical specimens and also compared the performance of platforms using 2 different technologies (pyrosequencing and real-time polymerase chain reaction) for both specimen types. METHODS Specimens from… CONTINUE READING
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Arcturus PicoPure DNA Extraction Kit handbook

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  • Mountain View, CA: Arcturus Bioscience,
  • 2012
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