Comparative study of cytokine release by human peripheral blood mononuclear cells stimulated with Streptococcus pyogenes superantigenic erythrogenic toxins, heat-killed streptococci, and lipopolysaccharide.

@article{MllerAlouf1994ComparativeSO,
  title={Comparative study of cytokine release by human peripheral blood mononuclear cells stimulated with Streptococcus pyogenes superantigenic erythrogenic toxins, heat-killed streptococci, and lipopolysaccharide.},
  author={Heide M{\"u}ller-Alouf and Joseph E. Alouf and D Gerlach and J{\"o}rg H Ozegowski and Catherine Fitting and J. M. Cavaillon},
  journal={Infection and immunity},
  year={1994},
  volume={62 11},
  pages={
          4915-21
        }
}
The differences between toxic or septic shocks in humans during infections by streptococci and gram-negative bacteria remain to be fully characterized. For this purpose, a quantitative study of the cytokine-inducing capacity of Streptococcus pyogenes erythrogenic (pyrogenic) exotoxins (ETs) A and C, heat-killed S. pyogenes bacteria, and Neisseria meningitidis endotoxin (lipopolysaccharide [LPS]) on human peripheral blood mononuclear cells (PBMC) and monocytes has been undertaken. The levels of… CONTINUE READING

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