Comparative study of brain CD8+ T cells induced by sporozoites and those induced by blood-stage Plasmodium berghei ANKA involved in the development of cerebral malaria.

@article{Bagot2004ComparativeSO,
  title={Comparative study of brain CD8+ T cells induced by sporozoites and those induced by blood-stage Plasmodium berghei ANKA involved in the development of cerebral malaria.},
  author={S{\'e}bastien Bagot and Fatima Nogueira and A. Collette and Virg{\'i}lio Est{\'o}lio do Ros{\'a}rio and François Lemonier and P. -A. Cazenave and Sylviane Pied},
  journal={Infection and immunity},
  year={2004},
  volume={72 5},
  pages={2817-26}
}
To obtain insight into the mechanisms that contribute to the pathogenesis of Plasmodium infections, we developed an improved rodent model that mimics human malaria closely by inducing cerebral malaria (CM) through sporozoite infection. We used this model to carry out a detailed study on isolated T cells recruited from the brains of mice during the development of CM. We compared several aspects of the immune response related to the experimental model of Plasmodium berghei ANKA infection induced… CONTINUE READING

From This Paper

Figures and tables from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Central nervous system in cerebral malaria : ‘ innocent bystander ’ or active participant in the induction of immunopathology ?

  • O. Bonduelle, M. Tefit, D. Seilhean, D. Mazier, B. Combadiere
  • Immunol . Cell Biol .
  • 2003

Similar Papers

Loading similar papers…