Comparative study of K channel behavior inβ cell lines with different secretory responses to glucose

@article{Eddlestone1989ComparativeSO,
  title={Comparative study of K channel behavior inβ cell lines with different secretory responses to glucose},
  author={G. T. Eddlestone and Bernard Ribalet and Sergio Ciani},
  journal={The Journal of Membrane Biology},
  year={1989},
  volume={109},
  pages={123-134}
}
The patch-clamp technique was used to identify and investigate two K channels in the cell membrane of the HIT cell, an insulin secreting cell line with glucose-sensitive secretion. Channel characteristics were compared with those of glucose-modulated K channels in the RINm5F cell, an insulin secreting cell line in which secretion is largely glucose… CONTINUE READING