Comparative studies on the iron chelators O-TRENSOX and TRENCAMS: selectivity of the complexation towards other biologically relevant metal ions and Al(3+).

@article{Biaso2002ComparativeSO,
  title={Comparative studies on the iron chelators O-TRENSOX and TRENCAMS: selectivity of the complexation towards other biologically relevant metal ions and Al(3+).},
  author={Fr{\'e}d{\'e}ric Biaso and P. Baret and J. L. Pierre and G. Serratrice},
  journal={Journal of inorganic biochemistry},
  year={2002},
  volume={89 1-2},
  pages={
          123-30
        }
}
  • Frédéric Biaso, P. Baret, +1 author G. Serratrice
  • Published 2002
  • Chemistry, Medicine
  • Journal of inorganic biochemistry
  • Complexation constants have been determined by potentiometric titration and spectrophotometric measurements for several biologically relevant divalent metals (Ca(2+), Cu(2+), Zn(2+)) as well as Al(3+) with the sulfonated tris(8-hydroxyquinolinate) tripodal ligand O-TRENSOX. The values demonstrate great selectivity of O-TRENSOX for Fe(3+) according to the sequence Fe(3+) >>Cu(2+)>Zn(2+)>Ca(2+). This selectivity is compared to that shown by tris(hydroxamate) and tris(catecholate) ligands. (1)H… CONTINUE READING
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    Iron mobilisation and cellular protection by a new synthetic chelator O-Trensox.
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