Comparative studies on the in vitro killing of human normal and leukemic clonogenic cells (CFUc) by daunorubicin, daunorubicinol, and daunorubicin-DNA complex

Abstract

The sensitivity of normal and acute nonlymphocytic leukemia-derived granulocytic stem cells (colony-forming units in culture, CFUc), exposed to daunorubicin, daunorubicinol, or daunorubicin-DNA complex in short-term suspension culture in vitro was studied. Normal CFUc were found to be considerably more sensitive to daunorubicin than to daunorubicinol… (More)
DOI: 10.1007/BF00253100

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