Comparative studies on the effects of toluidine blue and methylene blue on the reduction of ferrihaemoglobin in man and dog

Abstract

In humans and in dogs, respectively, about 30 and 60% of the haemoglobin was oxidized to ferrihaemoglobin by intravenous injection of 4-dimethylaminophenol hydrochloride. Toluidine blue was found to accelerate the subsequent reduction of ferrihaemoglobin in dogs 2–3 times more rapidly than methylene blue. In man toluidine blue 2 mg/kg was about twice as… (More)
DOI: 10.1007/BF00562507

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