Comparative studies on mucosal and intravenous transmission of simian immunodeficiency virus (SIVsm): the kinetics of evolution to neutralization resistance are related to progression rate of disease.

Abstract

The kinetics of appearance of autologous neutralizing antibodies were studied in cynomolgus macaques infected with simian immunodeficiency virus (SIVsm) by the intravenous (IV) route (six monkeys) or the intrarectal (IR) route (ten monkeys). The SIVsm inoculum virus and reisolates obtained at 2 weeks, 3 or 4 months and later than 1 year were tested in a… (More)

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@article{Laurn2006ComparativeSO, title={Comparative studies on mucosal and intravenous transmission of simian immunodeficiency virus (SIVsm): the kinetics of evolution to neutralization resistance are related to progression rate of disease.}, author={Anna Laur{\'e}n and Rigmor Thorstensson and Eva M{\'a}ria Feny{\"o}}, journal={The Journal of general virology}, year={2006}, volume={87 Pt 3}, pages={595-606} }