Comparative studies of the colony-promoting activity of porcine kidney extract with several interleukins and colony-stimulating factors.

@article{Kashiwakura1991ComparativeSO,
  title={Comparative studies of the colony-promoting activity of porcine kidney extract with several interleukins and colony-stimulating factors.},
  author={Ikuo Kashiwakura and Yukitoshi Hayase and Yoshinari Takagi},
  journal={Chemical & pharmaceutical bulletin},
  year={1991},
  volume={39 6},
  pages={1495-8}
}
Porcine kidney extracts (PKE) possess colony-promoting activity (CPA) which stimulates primitive hematopoietic cells in the presence of granulocyte/macrophage colony-stimulating factor (GM-CSF), but PKE itself does not stimulate colony formation on murine bone marrow cells. We have compared the CPA of PKE with that of recombinant cytokines or CSFs such as interleukin-1 alpha (IL-1 alpha), IL-3, IL-6, granulocyte colony-stimulating factor (G-CSF), GM-CSF and macrophage colony-stimulating factor… CONTINUE READING