Comparative studies of osteoblast and fibroblast type I collagen in a patient with osteogenesis imperfecta type IV.

@article{Galicka2002ComparativeSO,
  title={Comparative studies of osteoblast and fibroblast type I collagen in a patient with osteogenesis imperfecta type IV.},
  author={Anna Galicka and Slawomir Wolczynski and Andrzej Gindzieński},
  journal={The Journal of pathology},
  year={2002},
  volume={196 2},
  pages={235-7}
}
The expression of type I collagen has been compared in fibroblast and osteoblast cultures of a patient with moderately severe osteogenesis imperfecta (OI) type IV, with respect to control cells. Electrophoretic analysis of type I collagen showed that both OI osteoblasts and fibroblasts synthesized normal chains and chains with delayed migration. However… CONTINUE READING