Comparative studies of lamivudine-zidovudine nanoparticles for the selective uptake by macrophages.

Abstract

The present study investigates the specific drug targeting of anti retroviral drugs, such as lamivudine and zidovudine, after intraperitoneal (i.p) injection by incorporation into polymeric nanoparticles (PNs) and solid lipid nanoparticles (SLNs). Our results showed that Glyceryl Monosterate-Poloxamer 188 SLNs (average diameter of 522.466 nm) showed slow… (More)

Topics

Cite this paper

@article{Sankar2012ComparativeSO, title={Comparative studies of lamivudine-zidovudine nanoparticles for the selective uptake by macrophages.}, author={V. Sankar and Parmar Nilaykumar Nareshkumar and Gohel Nishit Ajitkumar and Shalini Devi Penmetsa and Sivaram Hariharan}, journal={Current drug delivery}, year={2012}, volume={9 5}, pages={506-14} }