Comparative studies of Toll-like receptor signalling using zebrafish.

  title={Comparative studies of Toll-like receptor signalling using zebrafish.},
  author={Zakia Kanwal and Geert Frits Wiegertjes and Wouter J. Veneman and Annemarie H. Meijer and Herman P. Spaink},
  journal={Developmental and comparative immunology},
  volume={46 1},
Zebrafish model systems for infectious disease are increasingly used for the functional analysis of molecular pattern recognition processes. These studies benefit from the high conservation level of all innate immune factors in vertebrates. Zebrafish studies are strategically well positioned for this because of the ease of comparisons with studies in other fish species of which the immune system also has been intensively studied, but that are currently still less amendable to detailed genetic… CONTINUE READING
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