Comparative sequences of the canine and feline vasopressin prohormones

Vasopressin (VP, antidiuretic hormone) is synthesized as a prohormone consisting of four domains: a signal sequence, the VP nonapeptide, neurophysin II (NP II), and a C-terminal glycopeptide. It plays a key role in cardiovascular homeostasis by regulating renal tubular water reabsorption and urine production. As part of our ongoing studies of the hormonal… (More)