• Biology, Medicine
  • Published in
    Bulletin of the World Health…
    1985

Comparative sensitivity of three mosquito cell lines for isolation of dengue viruses.

@article{Kuno1985ComparativeSO,
  title={Comparative sensitivity of three mosquito cell lines for isolation of dengue viruses.},
  author={Goro Kuno and Duane J. Gubler and M. Velez and A Oliver},
  journal={Bulletin of the World Health Organization},
  year={1985},
  volume={63 2},
  pages={
          279-86
        }
}
Comparative studies were carried out on three mosquito cell lines (C6/36 clone of Aedes albopictus, AP-61 from A. pseudoscutellaris, and TRA-284 from Toxorhynchites amboinensis) to determine their sensitivity to dengue virus isolation, growth, and handling characteristics for immunofluorescent testing. Virus isolation rates from human sera were the highest in the TRA-284-SF (a line adapted to serum-free medium), followed by the TRA-284 parental line and AP-61. Virus isolation was the lowest in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 39 CITATIONS