Comparative scaffolding and gap filling of ancient bacterial genomes applied to two ancient Yersinia pestis genomes

@inproceedings{Luhmann2017ComparativeSA,
  title={Comparative scaffolding and gap filling of ancient bacterial genomes applied to two ancient Yersinia pestis genomes},
  author={Nina Luhmann and Daniel Doerr and C{\'e}dric Chauve},
  booktitle={Microbial genomics},
  year={2017}
}
Yersinia pestis is the causative agent of the bubonic plague, a disease responsible for several dramatic historical pandemics. Progress in ancient DNA (aDNA) sequencing rendered possible the sequencing of whole genomes of important human pathogens, including the ancient Y. pestis strains responsible for outbreaks of the bubonic plague in London in the 14th century and in Marseille in the 18th century, among others. However, aDNA sequencing data are still characterized by short reads and non… CONTINUE READING
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