Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture.

@article{Keelan1994ComparativeRO,
  title={Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture.},
  author={Jeffrey A Keelan and Yunling Song and J. T. France},
  journal={Placenta},
  year={1994},
  volume={15 8},
  pages={803-18}
}
In the present study, we investigated the roles of cyclic adenosine monophosphate (cAMP), intracellular calcium, glucocorticoids, protein kinase-C and gonadotrophin-releasing hormone (GnRH) in regulating human chorionic gonadotrophin (hCG), inhibin and activin production in cultured human term placental trophoblast cells. Inhibin and hCG were measured in conditioned media by radioimmunoassay, while putative forms of inhibin and activin were characterized by western blotting using affinity… CONTINUE READING

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