Comparative recombination rates in the rat, mouse, and human genomes.

  title={Comparative recombination rates in the rat, mouse, and human genomes.},
  author={Michael Ignatius Jensen-Seaman and Terrence S. Furey and Bret A Payseur and Yontao Lu and Krishna M. Roskin and Chin-Fu Chen and Michael A. Thomas and David Haussler and Howard J. Jacob},
  journal={Genome research},
  volume={14 4},
Levels of recombination vary among species, among chromosomes within species, and among regions within chromosomes in mammals. This heterogeneity may affect levels of diversity, efficiency of selection, and genome composition, as well as have practical consequences for the genetic mapping of traits. We compared the genetic maps to the genome sequence assemblies of rat, mouse, and human to estimate local recombination rates across these genomes. Humans have greater overall levels of… CONTINUE READING
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