Comparative pulmonary toxicity study of nano-TiO(2) particles of different sizes and agglomerations in rats: different short- and long-term post-instillation results.

@article{Kobayashi2009ComparativePT,
  title={Comparative pulmonary toxicity study of nano-TiO(2) particles of different sizes and agglomerations in rats: different short- and long-term post-instillation results.},
  author={Norihiro Kobayashi and Masato Naya and Shigehisa Endoh and Junko Maru and Kazuhiro Yamamoto and Junko Nakanishi},
  journal={Toxicology},
  year={2009},
  volume={264 1-2},
  pages={110-8}
}
Two intratracheal instillation experiments with nano-size titanium dioxide (TiO(2)) particles of different sizes and agglomerations were conducted in rats to compare the biological responses induced by the different particles. In experiment 1, 5 mg/kg of nano-TiO(2) particles of different primary sizes was intratracheally instilled in rats. In experiment 2, a similar procedure was followed with 5 mg/kg of nano-TiO(2) particles of the same primary sizes but different agglomerations in liquid… CONTINUE READING

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