Comparative proteomics profiling reveals role of smooth muscle progenitors in extracellular matrix production.


OBJECTIVE Recent studies on cardiovascular progenitors have led to a new appreciation that paracrine factors may support the regeneration of damaged tissues. METHODS AND RESULTS We used a shotgun proteomics strategy to compare the secretome of peripheral blood-derived smooth muscle progenitors (SPCs) with human aortic smooth muscle cells. The late… (More)
DOI: 10.1161/ATVBAHA.110.204651