Comparative proteomics of small cell lung carcinoma.

  title={Comparative proteomics of small cell lung carcinoma.},
  author={Tamar Ziv and Eilon Barnea and Hava Segal and Rivka Sharon and Ilan Beer and Arie Admon},
  journal={Cancer biomarkers : section A of Disease markers},
  volume={2 6},
Small cell lung carcinoma (SCLC) is an aggressive, highly metastatic cancer with a strong tendency for chemotherapy resistance. Identification of proteins uniquely expressed in SCLC cells, can facilitate the development of new diagnostic tools, improve immunotherapy, and deepen our understanding of the underlying mechanisms of the disease. Here we describe a comparative proteomics analysis of ten SCLC cell lines and three controls lines, while searching for proteins preferentially expressed in… CONTINUE READING