Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects.

@article{Castao2006ComparativePO,
  title={Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects.},
  author={Eduardo Miguel Casta{\~n}o and Alex E. Roher and Chera L Esh and Tyler A. Kokjohn and Thomas Gerald Beach},
  journal={Neurological research},
  year={2006},
  volume={28 2},
  pages={155-63}
}
OBJECTIVES Diagnostic tests able to reveal Alzheimer's disease (AD) in living patients before cognitive ability is destroyed are urgently needed. Such tests must distinguish AD from other dementia causes, as well as differentiate subtle changes associated with normal aging from true pathology emergence. A single biomarker offering such diagnostic and prognostic capacities has eluded identification. Therefore, a valuable test for AD is likely to be based on a specific pattern of change in a set… CONTINUE READING