Comparative proteomic profiling of plasma very-low-density and low-density lipoproteins.

@article{Sun2010ComparativePP,
  title={Comparative proteomic profiling of plasma very-low-density and low-density lipoproteins.},
  author={Hung-Yu Sun and Sun-Fang Chen and M D Lai and Ting-Tsung Chang and Tz-Li Chen and Pei-Yu Li and Dar-Bin Shieh and K Young},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2010},
  volume={411 5-6},
  pages={336-44}
}
BACKGROUND Low-density lipoprotein (LDL) is a natural metabolite of very-low-density lipoprotein (VLDL) in the circulation. Systematic investigation of total protein components and dynamics might provide insights into this normal metabolic process. METHODS VLDL and LDL were purified from normolipidemia pooled plasma by gradient ultracentrifugation with either ionic or non-ionic media. The protein contents were compared by liquid chromatography tandem mass analyses based on isobaric tag for… CONTINUE READING