Comparative proteomic analysis of mouse livers from embryo to adult reveals an association with progression of hepatocellular carcinoma.

Abstract

To identify potential oncofetal biomarkers that distinguish hepatocellular carcinoma (HCC) from healthy liver tissues, we compared and analyzed the proteomic profiles of mouse livers at different developmental stages. Fetal (E13.5, E16.5), newborn (NB), postnatal (3-week) and adult (3-month) livers were isolated and profiled by 2-D PAGE. Statistical… (More)
DOI: 10.1002/pmic.200700590

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@article{Lee2008ComparativePA, title={Comparative proteomic analysis of mouse livers from embryo to adult reveals an association with progression of hepatocellular carcinoma.}, author={Nikki P. Y. Lee and Kar-wai Leung and Nicole W. T. Cheung and Brian Yee Hong Lam and Michelle Z Xu and Pak C. Sham and George K. K. Lau and Ronnie T. P. Poon and Sheung-tat Fan and John Moon Ching Luk}, journal={Proteomics}, year={2008}, volume={8 10}, pages={2136-49} }