Comparative proteomic analysis of human somatic cells, induced pluripotent stem cells, and embryonic stem cells.

@article{Kim2012ComparativePA,
  title={Comparative proteomic analysis of human somatic cells, induced pluripotent stem cells, and embryonic stem cells.},
  author={Sun Young Kim and Min-Jeong Kim and Hyeyun Jung and Won Kon Kim and Sang Oh Kwon and Myung Jin Son and Ik-Soon Jang and Jong-Soon Choi and Sung Goo Park and Byoung Chul Park and Y Han and Sang Chul Lee and Yee Sook Cho and K H Bae},
  journal={Stem cells and development},
  year={2012},
  volume={21 8},
  pages={1272-86}
}
Induced pluripotent stem cells (iPSCs) are somatic cells that have been reprogrammed to a pluripotent state via introduction of defined transcription factors. iPSCs are a valuable resource for regenerative medicine, but whether iPSCs are identical to embryonic stem cells (ESCs) remains unclear. In this study, we performed comparative proteomic analyses of human somatic cells [human newborn foreskin fibroblasts (hFFs)], human iPSCs (hiPSCs) derived from hFFs, and H9 human ESCs (hESCs). We… CONTINUE READING

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