Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia

@article{Edgar2000ComparativePA,
  title={Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia},
  author={Paul F Edgar and James E Douglas and Garth J S Cooper and Brian Dean and Robert Kydd and Richard L. M. Faull},
  journal={Molecular Psychiatry},
  year={2000},
  volume={5},
  pages={85-90}
}
Comparative brain proteome analysis is a new strategy to discover proteins and therefore genes whose altered expression may underlie schizophrenia. This strategy does not require an a priori theory of the pathogenesis or the mode of inheritance of schizophrenia. Using proteome analysis we previously compared the hippocampal proteome, that is, those proteins expressed by the hippocampal genome, of seven schizophrenic individuals with the hippocampal proteome of seven control individuals, matched… CONTINUE READING