Comparative protein structure modeling using MODELLER.

@article{Eswar2007ComparativePS,
  title={Comparative protein structure modeling using MODELLER.},
  author={Narayanan Eswar and B. Webb and Marc A. Mart{\'i}-Renom and Mallur S. Madhusudhan and David Eramian and Min-yi Shen and Ursula Pieper and Andrej Sali},
  journal={Current protocols in protein science},
  year={2007},
  volume={Chapter 2},
  pages={
          Unit 2.9
        }
}
Functional characterization of a protein sequence is a common goal in biology, and is usually facilitated by having an accurate three-dimensional (3-D) structure of the studied protein. In the absence of an experimentally determined structure, comparative or homology modeling can sometimes provide a useful 3-D model for a protein that is related to at least one known protein structure. Comparative modeling predicts the 3-D structure of a given protein sequence (target) based primarily on its… CONTINUE READING
Highly Cited
This paper has 24 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Protein structure fitting and refinement guided by cryo-EM density.

Structure • 2008
View 7 Excerpts
Method Support
Highly Influenced

Adaptive evolution of signaling partners.

Molecular biology and evolution • 2015
View 1 Excerpt
Highly Influenced

Computer-Based Methods of Inhibitor Prediction

View 3 Excerpts
Method Support
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Crystal structure of a GCN 5related N - acetyltransferase : Serratia marcescens aminoglycoside 3N - acetyltransferase

K. C. Worley, P. Culpepper, B. A. Wiese, R. F. Smith
Cell • 1998
View 2 Excerpts
Highly Influenced

Scoring profiletoprofile sequence alignments

E. Wolf, A. Vassilev, +3 authors S. K. Burley
Protein Sci . • 2004