Comparative properties of untreated andN-nitrosobenzylmethyl-amine-transformed rat esophageal epithelial cell lines

@article{Stoner1989ComparativePO,
  title={Comparative properties of untreated andN-nitrosobenzylmethyl-amine-transformed rat esophageal epithelial cell lines},
  author={Gary David Stoner and Merrill S. Babcock and Maureen M. Mc Corquodale and William T Gunning and Roubadeh Jamasbi and Neilma Budd and Bharati Hukku},
  journal={In Vitro Cellular & Developmental Biology},
  year={1989},
  volume={25},
  pages={899-908}
}
A culture system utilizing rat esophageal epithelial cells has been developed. Four normal and eightN-nitrosobenzylmethylamine-treated lines were compared with respect to chromosome number, anchorage-independent growth in agarose, and tumorigenic potential in syngenic rats. All cell lines were aneuploid with nine in the near-tetraploid range and three in the near-diploid range. No relation between tumorigenic potential and chromosome number or structure was apparent. Similarly, anchorage… CONTINUE READING
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