Comparative plasma pharmacokinetics of ceftiofur sodium and ceftiofur crystalline-free acid in neonatal calves.

@article{Woodrow2016ComparativePP,
  title={Comparative plasma pharmacokinetics of ceftiofur sodium and ceftiofur crystalline-free acid in neonatal calves.},
  author={J S Woodrow and Marc Caldwell and Sherry Cox and Murray E. Hines and Brent C Credille},
  journal={Journal of veterinary pharmacology and therapeutics},
  year={2016},
  volume={39 3},
  pages={271-6}
}
The objective of this study was to compare the plasma pharmacokinetic profile of ceftiofur crystalline-free acid (CCFA) and ceftiofur sodium in neonatal calves between 4 and 6 days of age. In one group (n = 7), a single dose of CCFA was administered subcutaneously (SQ) at the base of the ear at a dose of 6.6 mg/kg of body weight. In a second group (n = 7), a single dose of ceftiofur sodium was administered SQ in the neck at a dose of 2.2 mg/kg of body weight. Concentrations of… CONTINUE READING