Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay.

@article{Kiernan2002ComparativePA,
  title={Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay.},
  author={Urban A. Kiernan and Kemmons A. Tubbs and Dobrin Nedelkov and Eric E. Niederkofler and Randall W. Nelson},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={297 2},
  pages={401-5}
}
Mass spectrometric immunoassay (MSIA) is a proteomics technology that combines the selectivity of affinity capture with the sensitivity and resolution of mass spectrometric detection. This unique approach allows for intact protein identification therefore is readily capable of discriminating between protein variants, i.e., mutations, posttranslational modifications, and truncations. In this work, MSIA is used in the comparative analyses of retinol binding protein (RBP) from the plasma and urine… CONTINUE READING