Comparative pharmacokinetics of zolpidem tartrate in five ethnic populations of China

  title={Comparative pharmacokinetics of zolpidem tartrate in five ethnic populations of China},
  author={Tao Guo and Guifu Mao and Longshan Zhao and Dongya Xia and Lu Yang},
  booktitle={Acta pharmaceutica Sinica. B},
The objective of this study was to evaluate the difference in the pharmacokinetics of zolpidem tatrate in subjects from five Chinese ethnicities (Han, Mongolian, Uigur, Korean and Hui). Healthy subjects (10 Hans, 10 Mongolians, 10 Uigurs, 10 Koreans and 9 Huis) were recruited and each received a 10 mg tablet-dose of zolpidem tatrate. A total of 12 plasma samples were collected over a 12 h period after administration. The concentrations of zolpidem in plasma were determined by an HPLC-FLU method… CONTINUE READING

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