Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats

@article{Pelser2002ComparativePO,
  title={Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration in rats},
  author={Andries Pelser and D. G. M{\"u}ller and J. du Plessis and J. D. du Preez and C. Goosen},
  journal={Biopharmaceutics \& Drug Disposition},
  year={2002},
  volume={23}
}
The intranasal route of administration provides a potential useful way of administering a range of systemic drugs. In order to assess the feasibility of this approach for the treatment of nausea and vomiting, doxylamine succinate was studied in rats for the pharmacokinetics (AUC, Cmax, tmax) following intranasal, oral and intravenous administrations. 
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