Comparative pharmacokinetics of aminoglycoside antibiotics in guinea pigs.

@article{Chung1982ComparativePO,
  title={Comparative pharmacokinetics of aminoglycoside antibiotics in guinea pigs.},
  author={Marilyn Chung and Luigi Parravicini and Borrouk M Assael and G. Cavanna and Elaine Radwanski and Samson Symchowicz},
  journal={Antimicrobial agents and chemotherapy},
  year={1982},
  volume={22 6},
  pages={1017-21}
}
The pharmacokinetics of netilmicin, gentamicin, and tobramycin in plasma and in perilymph of guinea pigs were studied after a single intravenous injection of 40 mg/kg. Detailed pharmacokinetic analysis of the plasma drug concentration-time data up to 36 h after the intravenous dose revealed that the pharmacokinetics of the aminoglycoside antibiotics can be… CONTINUE READING