Comparative performance of urinary lipoarabinomannan assays and Xpert MTB/RIF in HIV-infected individuals.

@article{Shah2014ComparativePO,
  title={Comparative performance of urinary lipoarabinomannan assays and Xpert MTB/RIF in HIV-infected individuals.},
  author={Maunank R. Shah and Willy Ssengooba and Derek T. Armstrong and Lydia Nakiyingi and Molly Holshouser and Jerrold J. Ellner and Moses Joloba and Yukari C. Manabe and Susan E. Dorman},
  journal={AIDS},
  year={2014},
  volume={28 9},
  pages={1307-14}
}
BACKGROUND Xpert MTB/RIF ('Xpert') and urinary lipoarabinomannan (LAM) assays offer rapid tuberculosis (TB) diagnosis, but have suboptimal sensitivity when used individually in HIV-positive patients. The yield of these tests used in combination for the diagnosis of active TB among HIV-infected TB suspects is unknown. DESIGN Study of comparative diagnostic accuracy nested into a prospective study of HIV-infected individuals with signs and/or symptoms of TB in Uganda. METHODS Xpert testing of… CONTINUE READING