Comparative pathogenesis of recombinant rabies vaccine strain SAD-L16 and SAD-D29 with replacement of Arg333 in the glycoprotein after peripheral inoculation of neonatal mice: less neurovirulent strain is a stronger inducer of neuronal apoptosis

Abstract

Less neurovirulent strains of rabies virus have been recognized to be stronger inducers of neuronal apoptosis in vitro than more neurovirulent strains, but few studies have clarified whether this also applies in vivo. A comparative study was performed in two-day-old ICR mice inoculated in a hindlimb thigh muscle with recombinant rabies virus vaccine strain… (More)
DOI: 10.1007/s00401-005-0006-z

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@article{Jackson2005ComparativePO, title={Comparative pathogenesis of recombinant rabies vaccine strain SAD-L16 and SAD-D29 with replacement of Arg333 in the glycoprotein after peripheral inoculation of neonatal mice: less neurovirulent strain is a stronger inducer of neuronal apoptosis}, author={Alan C Jackson and Pamini Rasalingam and Simon Chioma Weli}, journal={Acta Neuropathologica}, year={2005}, volume={111}, pages={372-378} }