Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity.

@article{Fleshman2018ComparativePA,
  title={Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity.},
  author={Amy Fleshman and Kristin E Mullins and Jason W. Sahl and Crystal M. Hepp and Nathan C Nieto and Kristin B. Wiggins and Heidie M. Hornstra and Daryl J. Kelly and Teik-Chye Chan and Rattanaphone Phetsouvanh and Sabine Dittrich and Phonepasith Panyanivong and Daniel H Paris and Paul Newton and Allen L. Richards and Talima Pearson},
  journal={Microbial genomics},
  year={2018}
}
Orientia tsutsugamushi, formerly Rickettsia tsutsugamushi, is an obligate intracellular pathogen that causes scrub typhus, an underdiagnosed acute febrile disease with high morbidity. Scrub typhus is transmitted by the larval stage (chigger) of Leptotrombidium mites and is irregularly distributed across endemic regions of Asia, Australia and islands of the… CONTINUE READING