Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes.

  • Michael Cimino
  • Published 2006 in Environmental and molecular mutagenesis

Abstract

National and international regulatory agencies historically have used genotoxicity information as part of a weight-of-evidence approach to evaluate potential human carcinogenicity. Additionally, some agencies consider heritable mutation a regulatory endpoint. Furthermore, genotoxicity has the potential to contribute to other adverse health conditions. This… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.