Comparative oral toxicity of coenzyme Q10 and its (2Z)-isomer in rats: single and four-week repeated dose toxicity studies.

@article{Hatakeyama2006ComparativeOT,
  title={Comparative oral toxicity of coenzyme Q10 and its (2Z)-isomer in rats: single and four-week repeated dose toxicity studies.},
  author={Shigeki Hatakeyama and Shigeo Kawase and Ikuo Yoshimura},
  journal={Journal of nutritional science and vitaminology},
  year={2006},
  volume={52 1},
  pages={9-20}
}
It has been reported that coenzyme Q10 (CoQ10) functions as an electron transfer carrier in mitochondria, and can produce an improvement in heart diseases such as congestive heart failure. Its (2Z)-isomer contains a cis-double bond at the 2-position of the decaprenyl side chain. As the original organic industrial synthesis of CoQ10 resulted in a product… CONTINUE READING